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Comorbid extra-intestinal central sensitization conditions worsen irritable bowel syndrome in primary care patients.
Authors
Wang XJ, Ebbert JO, Loftus CG, Rosedahl JK, Philpot LMAbstract
Irritable bowel syndrome (IBS) is characterized as a central sensitization syndrome (CSS), a group of conditions including fibromyalgia, chronic fatigue, and restless leg syndrome (RLS) among others with frequent comorbidities of anxiety, depression, and chemical sensitivity. The prevalence of comorbid conditions and their impact on IBS symptom severity and quality of life in rural community populations has not been described.