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Papers of the Week


Papers: 22 Apr 2023 - 28 Apr 2023

RESEARCH TYPE:
Commentary/Perspective


Human Studies

PAIN TYPE:
Neuropathic Pain


2023 Apr 21


BMJ


37085164


381

Combination therapy for painful diabetic neuropathy is safe and effective.

Authors

Saul H, Deeney B, Imison C, Tesfaye S

Abstract

The study Tesfaye S, Sloan G, Petrie J, et al. Comparison of amitriptyline supplemented with pregabalin, pregabalin supplemented with amitriptyline, and duloxetine supplemented with pregabalin for the treatment of diabetic peripheral neuropathic pain (OPTION-DM): a multicentre, double-blind, randomised crossover trial. 2022;400:680-90.To read the full NIHR Alert, go to: https://evidence.nihr.ac.uk/alert/combination-therapy-for-painful-diabetic-neuropathy-is-safe-and-effective/.