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Papers of the Week

Papers: 3 Jun 2023 - 9 Jun 2023

Methodology, Translational

Human Studies, Molecular/Cellular, Neurobiology

2023 Jun 06

Eur J Pain


Cold-evoked potentials in clinical practice: A head-to-head contrast with laser-evoked responses.


Perchet C, Hagiwara K, Salameh C, Garcia-Larrea L


Innocuous cooling of the skin activates cold-specific Aδ fibres, and hence, the recording of cold-evoked potentials (CEPs) may improve the objective assessment of human thermo-nociceptive function. While the feasibility of CEP recordings in healthy humans has been reported, their reliability and diagnostic use in clinical conditions have not been documented.