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Papers of the Week


Papers: 26 Aug 2023 - 1 Sep 2023

RESEARCH TYPE:
Clinical


Human Studies, Neurobiology, Pharmacology/Drug Development

PAIN TYPE:
Arthritis, Inflammation/Inflammatory


2023 Aug 29


Osteoarthritis Cartilage


37652258

Characterization of adverse joint outcomes in patients with osteoarthritis treated with subcutaneous tanezumab.

Authors

Carrino JA, McAlindon TE, Schnitzer TJ, Guermazi A, Hochberg MC, Conaghan PG, Brown MT, Burr A, Fountaine RJ, Pixton GC, Viktrup L, Verburg KM, West C

Abstract

Due to the risk of rapidly progressive osteoarthritis (RPOA), the phase III studies of subcutaneous (SC) tanezumab in patients with moderate to severe hip or knee osteoarthritis (OA) included comprehensive joint safety surveillance. This pooled analysis summarizes these findings.