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Papers of the Week


Papers: 11 Jan 2025 - 17 Jan 2025


2025 Jan 12


J Adv Res


39809361

CDK8 mediated inflammatory microenvironment aggravates osteoarthritis progression.

Authors

Lin Z, Xu Y, Jiang H, Zeng W, Wang Y, Zhu L, Lin C, Lou C, Shen H, Ye H, Gu Y, Yu H, Pan X, Zheng L

Abstract

Cyclin-Dependent Kinase 8 (CDK8), a CDK family member, regulates the development of inflammatory processes through transcriptional activation. The involvement of CDK8 in osteoarthritis (OA) progression is not yet understood.