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Papers of the Week

Papers: 20 Jan 2024 - 26 Jan 2024


Front Immunol



Causal relationship between the blood immune cells and intervertebral disc degeneration: univariable, bidirectional and multivariable Mendelian randomization.


Qin C, Chen M, Yu Q, Wang X, Hu T, Lei B, Yan Z, Cheng S


Intervertebral disc degeneration (IVDD) is a prominent contributor to chronic low back pain, impacting millions of individuals annually. Current research on disc degeneration is placing a growing emphasis on the role of the immune system in this process. Nevertheless, the precise relationship between immunity and disc degeneration remains to be fully elucidated.