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Papers of the Week


Papers: 5 Aug 2023 - 11 Aug 2023

RESEARCH TYPE:
Clinical


Human Studies, Medical Devices, Neurobiology, Neuromodulation

PAIN TYPE:
Musculoskeletal Pain


2023 Aug 02


Brain Stimul


37541579

BurstDR spinal cord stimulation rebalances pain input and pain suppression in the brain in chronic neuropathic pain.

Authors

Vanneste S, De Ridder D

Abstract

Chronic pain is processed by at least three well-known pathways, two pain provoking pathways including a medial ‘suffering’ and lateral ‘painfulness’ pathway. A third descending pain pathway modulates pain but is predominantly inhibitory. Chronic pain can be seen as an imbalance between the two pain-provoking and the pain inhibitory pathways. If this assumption is correct, then the imbalance between pain input and pain suppression should reverse and normalize in response to successful, i.e., pain reducing burstDR spinal cord stimulation, one of the current treatment options for neuropathic pain.