Browse by Audience
Skip to content
Papers of the Week
Brainstem modulation of nociception by periaqueductal gray neurons expressing the mu-opioid receptor in mice.
Authors
Nguyen E, Chiang MC, Nguyen C, Ross SEAbstract
Pharmacological manipulations directed at the periaqueductal gray have demonstrated the importance of the mu-opioid receptor in modulating reflexive responses to nociception. We hypothesized that a supraspinal pathway centered on neurons in the periaqueductal gray containing the mu-opioid receptor could modulate nociceptive and itch behaviors.