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Papers of the Week

Papers: 19 Aug 2023 - 25 Aug 2023


Human Studies, Neurobiology, Neuromodulation

2023 Aug 19

Eur J Pain


Beyond trial-and-error: Individualizing therapeutic transcranial neuromodulation for chronic pain.


Ciampi de Andrade D, García-Larrea L


Repetitive transcranial magnetic stimulation (rTMS) applied to the motor cortex provides supplementary relief for some individuals with chronic pain who are refractory to pharmacological treatment. As rTMS slowly enters treatment guidelines for pain relief, its starts to be confronted with challenges long known to pharmacological approaches: efficacy at the group-level does not grant pain relief for a particular patient. In this review, we present and discuss a series of ongoing attempts to overcome this therapeutic challenge in a personalized medicine framework.