I am a
Home I AM A Search Login

Papers of the Week


Papers: 6 Jan 2024 - 12 Jan 2024


2024 Jan 10


Cell Host Microbe


38211562


32


1

Better than being aPARt: S. aureus itches to get close to sensory neurons.

Authors

Chen Z, Huang S, Su Y

Abstract

In a recent issue of Cell, Deng et al. show that S. aureus serine protease V8 triggers itch, independent of inflammation, by activating sensory neurons through PAR1. This study presents mechanistic insights into pruritogenic bacteria and their interactions with sensory neurons while providing a possible approach for treating itch-related diseases.