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Papers of the Week

Papers: 11 May 2024 - 17 May 2024


Front Mol Neurosci



Behavioral and pharmacological characterization of planarian nociception.


Reho G, Menger Y, Goumon Y, Lelièvre V, Cadiou H


Pain mostly arises because specialized cells called nociceptors detect harmful or potentially harmful stimuli. In lower animals with less convoluted nervous system, these responses are believed to be purely nociceptive. Amongst invertebrate animal models, planarians are becoming popular in a wide range of pharmacological and behavioral studies beyond the field of regeneration. Recent publications led the way on pain studies by focusing on nociceptive behaviors such as the ‘scrunching’ gait displayed under various noxious stimuli, as opposed to the ‘gliding’ gait planarians usually adopt in normal conditions.