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Papers of the Week


Papers: 10 Jun 2023 - 16 Jun 2023

RESEARCH TYPE:
Clinical


Human Studies, Neurobiology, Pharmacology/Drug Development

PAIN TYPE:
Psychological/Comorbidities


2023 Jun 14


JAMA Surg


37314800

Editor's Pick

Association of Intraoperative Opioid Administration With Postoperative Pain and Opioid Use.

Authors

Santa Cruz Mercado LA, Liu R, Bharadwaj KM, Johnson JJ, Gutierrez R, Das P, Balanza G, Deng H, Pandit A, Stone TAD, Macdonald T, Horgan C, Tou SLJ, Houle TT, Bittner EA, Purdon PL

Abstract

Opioids administered to treat postsurgical pain are a major contributor to the opioid crisis, leading to chronic use in a considerable proportion of patients. Initiatives promoting opioid-free or opioid-sparing modalities of perioperative pain management have led to reduced opioid administration in the operating room, but this reduction could have unforeseen detrimental effects in terms of postoperative pain outcomes, as the relationship between intraoperative opioid usage and later opioid requirements is not well understood.