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Papers of the Week


Papers: 15 Mar 2025 - 21 Mar 2025


2025 Mar 14


Headache


40084674

Assessing blood pressure changes and hypertension-related outcomes in patients with migraine treated with erenumab: A systematic review and meta-analysis.

Authors

Makita LM, de Kleimmann RF, de Oliveira RR, Neves HAF, Corso AMS, Alves VS, Kojima GSA, Koppanatham A, Kowacs PA, Piovesan EJ

Abstract

We aimed to systematically review and summarize evidence on the effects of erenumab on systemic blood pressure (BP) in patients with migraine (International Prospective Register of Systematic Reviews ID: CRD42024571056). US Prescribing Information for erenumab was updated to include the potential risk of hypertension, although randomized trials did not link it previously. The association of this monoclonal antibody with an elevated vascular risk remains uncertain.