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Papers of the Week


Papers: 19 Aug 2023 - 25 Aug 2023

RESEARCH TYPE:
Basic Science


Animal Studies, Molecular/Cellular, Neurobiology, Pharmacology/Drug Development

PAIN TYPE:
Inflammation/Inflammatory


2023 Aug 24


Eur J Pain


37615256

Antinociceptive effects of nefopam activating descending serotonergic modulation via 5-HT2 receptors in the nucleus raphe magnus.

Authors

Li Y, Kim WM, Lee YJ, Kang DH, Lee HG, Choi JI, Yoon MH

Abstract

Nefopam is a centrally acting antinociceptive drug; however, the underlying mechanisms are not fully understood. This study investigated the supraspinal mechanisms of nefopam.