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Papers of the Week


Papers: 18 Nov 2023 - 24 Nov 2023


2023


PLoS One


37972114


18


11

Anethole attenuates motor dysfunctions, striatal neuronal activity deficiency and blood brain barrier permeability by decreasing striatal α-synuclein and oxidative stress in rotenone-induced Parkinson’s disease of male rats.

Authors

Moradi Vastegani S, Khoshnam SE, Ghafouri S, Bakhtiari N, Farbood Y, Sarkaki A

Abstract

Anethole is the main compound of the essential oil of anise and several other plants, which has antioxidant, anti-inflammatory, and neuroprotective properties. Oxidative stress is considered as an important factor in the pathogenesis of PD. In the present study, we aimed to investigate the effects of anethole against rotenone-induced PD.