I am a
Home I AM A Search Login

Papers of the Week

Papers: 8 Jun 2024 - 14 Jun 2024

2024 Jun 07

Expert Opin Ther Pat


An updated patent review of TRPA1 antagonists (2020 – present).


Vitale RM, de Petrocellis L, Amodeo P


TRPA1 is a nonselective calcium channel, member of the transient receptor potential (TRP) superfamily, also referred to as the ‘irritant’ receptor, being activated by pungent and noxious exogenous chemicals as well as by endogenous algogenic stimuli, to elicit pain, itch and inflammatory conditions. For this reason, it is considered an attractive therapeutic target to treat as wide range of diseases including acute and chronic pain, itch, and inflammatory airway diseases.