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Papers of the Week


Papers: 25 Feb 2023 - 3 Mar 2023

RESEARCH TYPE:
Clinical


Human Studies, Molecular/Cellular, Pharmacology/Drug Development

PAIN TYPE:
Migraine/Headache


2023 Mar 01


Eur J Neurol


36856538

An observational study on monoclonal antibodies against CGRP and its receptor.

Authors

Schiano di Cola F, Bolchini M, Ceccardi G, Caratozzolo S, Liberini P, Rao R, Padovani A

Abstract

Based on their pharmacological target, two classes of calcitonin gene-related peptide (CGRP) monoclonal antibodies (mAbs) have been identified: antibodies against the CGRP ligand – Galcanezumab, Fremanezumab, Eptinezumab – and the CGRP receptor (CGRP-R), Erenumab. Aim of the present study was to compare anti-CGRP versus anti-CGRP-R mAbs in patients with high frequency episodic and chronic migraine.