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Altered pain processing and sensitization in sickle cell disease: a scoping review of quantitative sensory testing findings.
Authors
Kenney MO, Knisley MR, McGill L, Campbell CAbstract
Over 50% of adults living with sickle cell disease have chronic pain, but the underlying mechanisms of chronic pain in this population remain unclear. Quantitative sensory testing is an important measurement tool for understanding pain and sensory processing. This scoping review summarizes quantitative sensory testing methodologies used in sickle cell studies and the evidence for central sensitization in this population.