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Papers of the Week


Papers: 15 Jun 2024 - 21 Jun 2024


2024 Jun 14


Cell Biosci


38877576


14


1

ALKBH5-mediated mA demethylation of Runx2 mRNA promotes extracellular matrix degradation and intervertebral disc degeneration.

Authors

Lei Y, Zhan E, Chen C, Hu Y, Lv Z, He Q, Wang X, Li X, Zhang F

Abstract

N6-methyladenosine (mA) methylation is a prevalent RNA modification implicated in various diseases. However, its role in intervertebral disc degeneration (IDD), a common cause of low back pain, remains unclear.