Browse by Audience
Skip to content
Papers of the Week
Age-associated changes in knee osteoarthritis, pain-related behaviors, and dorsal root ganglia immunophenotyping of male and female mice.
Authors
Geraghty T, Obeidat AM, Ishihara S, Wood MJ, Li J, Lopes EBP, Scanzello CR, Griffin TM, Malfait AM, Miller REAbstract
Osteoarthritis (OA) is a leading cause of chronic pain, yet OA pain management remains poor. Age is the strongest predictor of OA development, and mechanisms driving OA pain are unclear. The goal of this study was to characterize age-associated changes in knee osteoarthritis, pain-related behaviors, and dorsal root ganglia (DRG) molecular phenotypes in mice of both sexes.