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Papers of the Week


Papers: 18 Feb 2023 - 24 Feb 2023

RESEARCH TYPE:
Basic Science


Animal Studies, Molecular/Cellular, Neurobiology

PAIN TYPE:
Abdominal/Pelvic Pain


2023 Feb 18


Dig Dis Sci


36808325

Activation of the High-Affinity Choline Transporter 1 in the Spinal Cord Relieves Stress-Induced Hyperalgesia.

Authors

Lin M, Hu G, Wang Z, Yu B, Tan W

Abstract

The mechanism underlying irritable bowel syndrome (IBS), a common disease with hyperalgesia, remains elusive. The spinal cholinergic system is involved in pain modulation, but its role in IBS is unknown.