Browse by Audience
Skip to content
Papers of the Week
Activation of central and peripheral transient receptor potential melastatin 8 increases susceptibility to spreading depolarization and facilitates trigeminal neuroinflammation.
Authors
Liu TT, Chen PY, Tseng CY, Chen YN, Chen JB, Ni TH, Wang SJ, Chen SP, Yen JCAbstract
Transient receptor potential melastatin 8 (TRPM8), a gene encoding a nonselective cation channel responsive to cold stimuli, has been implicated in migraine susceptibility. Despite this association, the role of TRPM8 to migraine pathogenesis remains elusive. This study aims to elucidate the potential role of TRPM8 in migraine pathophysiology.