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Papers of the Week


Papers: 15 Jul 2023 - 21 Jul 2023

RESEARCH TYPE:
Review


Human Studies, Molecular/Cellular

PAIN TYPE:
Migraine/Headache


2023


Front Mol Neurosci


37456527


16

A systematic literature review on the role of glial cells in the pathomechanisms of migraine.

Authors

Zhang S, Azubuine J, Schmeer C

Abstract

The pathomechanisms underlying migraine are intricate and remain largely unclear. Initially regarded as a neuronal disorder, migraine research primarily concentrated on understanding the pathophysiological changes within neurons. However, recent advances have revealed the significant involvement of neuroinflammation and the neuro-glio-vascular interplay in migraine pathogenesis.