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Papers of the Week


Papers: 26 Oct 2024 - 1 Nov 2024


2024 Oct 26


Drugs


39455546

A Meta-analysis Exploring the Efficacy of Neuropathic Pain Medication for Low Back Pain or Spine-Related Leg Pain: Is Efficacy Dependent on the Presence of Neuropathic Pain?

Authors

Ward J, Grinstead A, Kemp A, Kersten P, Schmid AB, Ridehalgh C

Abstract

Highly variable pain mechanisms in people with low back pain or spine-related leg pain might contribute to inefficacy of neuropathic pain medication. This meta-analysis aimed to determine how neuropathic pain is identified in clinical trials for people taking neuropathic pain medication for low back pain or spine-related leg pain and whether subgrouping based on the presence of neuropathic pain influences efficacy.