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Papers of the Week

2023 Feb 03

World Neurosurg

Continuous epidural saline infusion for the treatment of spontaneous intracranial hypotension.


Onuma K, Yanaka K, Nakamura K, Takahashi N, Tajima K, Watanabe D, Ishikawa E
World Neurosurg. 2023 Feb 03.
PMID: 36739897.


Spontaneous intracranial hypotension (SIH) is an increasingly recognized cause of orthostatic headache but treatment strategies remain controversial. The epidural blood patch (EBP) is a well-known and widely used treatment in patients with conservative treatment-resistant SIH but symptoms may not improve even after multiple EBPs and resistant patients suffer from a lack of appropriate treatment options. Therefore, this study assessed the safety and efficacy of continuous epidural saline infusion (CESI) for SIH treatment.