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Papers of the Week

2023 Feb 03

J Neuroinflammation



Hydrogen attenuates postoperative pain through Trx1/ASK1/MMP9 signaling pathway.


Li J, Ruan S, Jia J, Li Q, Jia R, Wan L, Yang X, Teng P, Peng Q, Shi Y-D, Yu P, Pan Y, Duan M-L, Liu W-T, Zhang L, Hu L
J Neuroinflammation. 2023 Feb 03; 20(1):22.
PMID: 36737785.


Postoperative pain is a serious clinical problem with a poorly understood mechanism, and lacks effective treatment. Hydrogen (H) can reduce neuroinflammation; therefore, we hypothesize that H may alleviate postoperative pain, and aimed to investigate the underlying mechanism.