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Papers of the Week


2022


Health Psychol Res


10


5

Brivaracetam to Treat Partial Onset Seizures in Adults.

Authors

Latimer D, Le D, Falgoust E, Ingraffia P, Abd-Elsayed A, Cornett EM, Singh R, Choi JH, Varrassi G, Kaye AM, Kaye AD, Ganti L
Health Psychol Res. 2022; 10(5):56782.
PMID: 36726475.

Abstract

Seizures are a hyperexcitable, and hypersynchronous imbalance between excitatory and inhibitory factors (E/I imbalance) in neurotransmission, and epilepsy is the recurrent manifestation of seizures within a reasonable time frame and without being attributable to a reversible cause. Brivaracetam is a derivative of the antiepileptic agent, levetiracetam, that is used as adjuvant therapy for focal onset seizures. It was approved by the FDA in 2016 and has shown promising results with minimal adverse effect reactions in clinical trials.