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Papers of the Week

2023 Jan-Apr

Case Rep Dermatol



A Rare Case of Prurigo Pigmentosa in a Danish Sibling Couple.


Danielsen M, Pallesen K, Riber-Hansen R, Bregnhøj A
Case Rep Dermatol. 2023 Jan-Apr; 15(1):26-30.
PMID: 36726802.


Prurigo pigmentosa (PP) is probably underdiagnosed due to lack of awareness. Previously, it was assumed that PP primarily affected Japanese females; however, more cases are reported worldwide, and the pathogenesis is still not completely understood. In this case report, we present two healthy Danish siblings, who developed PP approximately 2 weeks after starting a ketogenic diet, suggesting that both increased levels of ketone bodies in the blood together with a genetic predisposition might play a role in the development of PP.