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Papers of the Week

2023 Jan

Eur Rev Med Pharmacol Sci



Dimethyl fumarate attenuates MSU-induced gouty arthritis by inhibiting NLRP3 inflammasome activation and oxidative stress.


Cao Y, Hu Y, Jin X-F, Liu Y, Zou J-M
Eur Rev Med Pharmacol Sci. 2023 Jan; 27(2):628-641.
PMID: 36734707.


Dimethyl fumarate (DMF) has shown anti-inflammatory and antioxidant activities. However, the effects of DMF on gouty arthritis remain elusive, and the underlying mechanism is not understood. In this study, we aim to investigate the role of DMF in gouty arthritis.