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Papers of the Week

2023 Feb 01

Br J Neurosurg

Spontaneous Shrinkage of isocitrate dehydrogenase (IDH)-mutant astrocytoma caused by intra-tumoural cyst rupture: a case report.


Suzuki R, Kanamori M, Saito R, Shimoda Y, Watanabe M, Tominaga T
Br J Neurosurg. 2023 Feb 01:1-5.
PMID: 36722392.


T2-fluid-attenuated inversion recovery (FLAIR) mismatch sign is a specific imaging finding of isocitrate dehydrogenase (IDH)-mutant astrocytomas. Histologically, a hypointense area on FLAIR images indicates the presence of microcysts. Here we report a case of IDH-mutant astrocytoma that shrunk spontaneously.