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Papers of the Week

2023 Jan 13



Khellin as a selective monoamine oxidase B inhibitor ameliorated paclitaxel-induced peripheral neuropathy in mice.


Ouyang X, Zhu D, Huang Y, Zhao X, Xu R, Wang J, Li WJ, Shen X
Phytomedicine. 2023 Jan 13; 111:154673.
PMID: 36716674.


Treatment of paclitaxel (PTX)-induced peripheral neuropathy (PIPN) is full of challenges because of the unclear pathogenesis of PIPN. Herbal folk medicine Khellin (Khe) is a natural compound extracted from Ammi visnaga for treatment of renal colics and muscle spasms.