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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / BACPAC: Protocol and Pilot Study Results for a Randomized Comparative Effectiveness Trial of Antidepressants, Fear Avoidance Rehabilitation, or the Combination for Chronic Low Back Pain and Comorbid High Negative Affect.

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2023 Jan 30


Pain Med


http://www.ncbi.nlm.nih.gov/pubmed/36715655?dopt=Abstract

BACPAC: Protocol and Pilot Study Results for a Randomized Comparative Effectiveness Trial of Antidepressants, Fear Avoidance Rehabilitation, or the Combination for Chronic Low Back Pain and Comorbid High Negative Affect.

Authors

BACPAC: Protocol and Pilot Study Results for a Randomized Comparative Effectiveness Trial of Antidepressants, Fear Avoidance Rehabilitation, or the Combination for Chronic Low Back Pain and Comorbid High Negative Affect.
Wasan AD, Edwards RR, Kraemer KL, Jeong J, Kenney M, Luong K, Cornelius MC, Mickles C, Dharmaraj B, Sharif E, Stoltenberg A, Emerick T, Karp JF, Bair MJ, George SZ, Hooten WM
Pain Med. 2023 Jan 30.
PMID: 36715655.

Abstract

Patients with chronic low back pain (CLBP) and comorbid depression or anxiety disorders are highly prevalent. Negative affect (NA) refers to a combination of negative thoughts, emotions, and behaviors. CLBP patients with high NA have greater pain, worse treatment outcomes, and greater prescription opioid misuse. We present the protocol for SYNNAPTIC- SYNergizing Negative Affect & Pain Treatment In Chronic pain.
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