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Papers of the Week

2023 Jan 20

Medicine (Baltimore)



Bone metastatic carcinoma with EGFR amplification and mutation: A case report and literature review.


Du H-J, Chen F-F, Liu Y, Zhou Y
Medicine (Baltimore). 2023 Jan 20; 102(3):e32615.
PMID: 36701708.


Mutations in the epidermal growth factor receptor (EGFR) gene are highly prevalent in non-small cell lung cancer, while rare in other cancers. Primarily it's hardly present in bone metastases from cancer of unknown primary (BMCUP). Currently, no specific treatment options for bone metastases from unknown primary cancers exist.