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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / Upregulation of the oxytocin receptors on peripheral sensory neurons mediated analgesia in chemotherapy-induced neuropathic pain.

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Papers: 21 Jan 2023 - 3 Feb 2023


2023 Jan 26


Br J Pharmacol


http://www.ncbi.nlm.nih.gov/pubmed/36702458?dopt=Abstract

Upregulation of the oxytocin receptors on peripheral sensory neurons mediated analgesia in chemotherapy-induced neuropathic pain.

Authors

Upregulation of the oxytocin receptors on peripheral sensory neurons mediated analgesia in chemotherapy-induced neuropathic pain.
Li L, Li P, Guo J, Wu Y, Zeng Q, Li N, Huang X, He Y, Ai W, Sun W, Liu T, Xiong D, Xiao L, Sun Y, Zhou Q, Kuang H, Wang Z, Jiang C
Br J Pharmacol. 2023 Jan 26.
PMID: 36702458.

Abstract

Currently, chemotherapy-induced neuropathic pain (CINP) has limited effective treatment. The roles of Oxytocin (OXT) and the oxytocin receptor (OXTR) in central analgesia have been well documented. However, the expression and function of OXTR in the peripheral nervous system remain unclear. Here, we evaluated the peripheral antinociceptive profiles of OXTR in CINP.
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