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Papers of the Week

2023 Dec

Eur J Gen Pract



Immediate release fentanyl in general practices: Mostly off-label prescribing.


Weesie YM, van Dijk L, Bouvy ML, Hek K
Eur J Gen Pract. 2023 Dec; 29(1):2165644.
PMID: 36695153.


The immediacy of the onset of opioids may be associated with the risk of dependency and accidental overdose. Nasal and oromucosal fentanyl dosage forms are so called immediate release fentanyl (IRF). These IRFs have been approved to treat breakthrough pain in patients with cancer who are on chronic opioid treatment only. There are signals of increased off-label prescribing of IRFs in general practices.