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Papers of the Week

Papers: 21 Jan 2023 - 3 Feb 2023


Front Mol Neurosci


The chronification mechanism of orofacial inflammatory pain: Facilitation by GPER1 and microglia in the rostral ventral medulla.


Zheng W, Huang X, Wang J, Gao F, Chai Z, Zeng J, Li S, Yu C
Front Mol Neurosci. 2022; 15:1078309.
PMID: 36683848.


Chronic orofacial pain is a common and incompletely defined clinical condition. The role of G protein-coupled estrogen receptor 1 (GPER1) as a new estrogen receptor in trunk and visceral pain regulation is well known. Here, we researched the role of GPER1 in the rostral ventral medulla (RVM) during chronic orofacial pain.