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Papers of the Week

2023 Jan 23


Tumefactive Demyelination in MOG Ab-Associated Disease, Multiple Sclerosis, and AQP-4-IgG-Positive Neuromyelitis Optica Spectrum Disorder.


Cacciaguerra L, Morris P, Tobin WO, Chen JJ, Banks SA, Elsbernd P, Redenbaugh V, Tillema J-M, Montini F, Sechi E, Lopez-Chiriboga SA, Zalewski N, Guo Y, Rocca MA, Filippi M, Pittock SJ, Lucchinetti C F, Flanagan EP
Neurology. 2023 Jan 23.
PMID: 36690455.


Studies on tumefactive brain lesions in myelin-oligodendrocyte-glycoprotein-IgG-associated disease (MOGAD) are lacking. We sought to characterize the frequency, clinical, laboratory, and MRI features of these lesions in MOGAD and compare them to multiple sclerosis (MS) and aquaporin-4-IgG-positive-neuromyelitis-optica-spectrum-disorder (AQP4+NMOSD).