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Papers of the Week

2023 Jan 20

JDR Clin Trans Res

The Opioid Analgesic Reduction Study (OARS) Pilot: A Double-Blind Randomized Multicenter Trial.


Feldman CA, Fredericks-Younger J, Desjardins PJ, Malmstrom H, Miloro M, Warburton G, Ward B, Ziccardi V, Fine DH, Greenberg P, Andrews T, Matheson PB, Lu S-E
JDR Clin Trans Res. 2023 Jan 20:23800844221144031.
PMID: 36680313.


With addiction rates and opioid deaths increasing, health care providers are obligated to help stem the opioid crisis. As limited studies examine the comparative effectiveness of fixed-dose combination nonopioid analgesia to opioid-containing analgesia, a comparative effectiveness study was planned and refined by conducting a pilot study.