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Papers of the Week

Papers: 14 Jan 2023 - 20 Jan 2023

2023 Jan 19

CNS Drugs

Switching OnabotulinumtoxinA to Monoclonal Anti-CGRP Antibodies in Drug-Resistant Chronic Migraine.


Iannone L F, Fattori D, Marangoni M, Benemei S, Chiarugi A, Geppetti P, De Cesaris F
CNS Drugs. 2023 Jan 19.
PMID: 36656298.


OnabotulinumtoxinA (BTX-A) and anti-calcitonin gene-related peptide (CGRP) monoclonal antibodies (anti-CGRP mAbs) are approved drugs for chronic migraine (CM), a difficult-to-treat condition. Optimization of CM patient management by choosing the best options and determining appropriate time for switching or adding concomitant treatments are highly needed.