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Papers: 14 Jan 2023 - 20 Jan 2023
Pharmacology/Drug Development
2023 Jan 17
Br J Pharmacol
Cannabinoids represent a promising therapeutic avenue for chronic pain, however clinical trials often fail to report analgesic efficacy of cannabinoids. Inhibition of voltage-gated calcium channels is one mechanism through which cannabinoids may produce analgesia. We hypothesized that cannabinoids and cannabinoid receptor agonists target different types of voltage gated calcium channels through distinct mechanisms.