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Papers of the Week

Papers: 14 Jan 2023 - 20 Jan 2023

2022 Dec 28

World J Gastroenterol



Bladder-colon chronic cross-sensitization involves neuro-glial pathways in male mice.


Atmani K, Wuestenberghs F, Baron M, Bouleté I, Guérin C, Bahlouli W, Vaudry D, do Rego J C, Cornu J-N, Leroi A-M, Coëffier M, Meleine M, Gourcerol G
World J Gastroenterol. 2022 Dec 28; 28(48):6935-6949.
PMID: 36632316.


Irritable bowel syndrome and bladder pain syndrome often overlap and are both characterized by visceral hypersensitivity. Since pelvic organs share common sensory pathways, it is likely that those syndromes involve a cross-sensitization of the bladder and the colon. The precise pathophysiology remains poorly understood.