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Papers of the Week

Papers: 14 Jan 2023 - 20 Jan 2023

Pharmacology/Drug Development

2023 Jan 01

Hepatol Commun



Impact of fentanyl analgesia on the accuracy of HVPG measurements in patients with cirrhosis: a prospective, multicenter study.


Zhang H, Yang L, Yu Z, Li D, Li L, Li S, Yan J, Li X
Hepatol Commun. 2023 Jan 01; 7(1):e0002.
PMID: 36633485.


HVPG measurement is the gold standard for assessing portal hypertension. Many patients decline HVPG measurements due to associated pain. According to previous studies, propofol sedation during HVPG measurements potentially alters HVPG readings. However, opioid analgesics' effects on HVPG await full elucidation. This study aimed to evaluate fentanyl analgesia's effects on HVPG measurement accuracy in patients with cirrhosis.