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Papers of the Week
A novel temperature-controlled laser system to uniformly activate cutaneous thermal receptors during movable thermal stimulation.
Abstract
Laser stimulators have been widely used in pain studies to selectively activate Aδ and C nociceptors without coactivation of mechanoreceptors. Temperature-controlled laser systems have been implemented with low-temperature variations during stimulations, however, these systems purely enabled stationary stimulation. This study aimed to implement, test and validate a new laser stimulation system that controls skin temperature by continuously adjusting laser output during stimulus movement to allow accurate investigation of tempo-spatial mechanisms in the nociceptive system.