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Papers of the Week

Papers: 7 Jan 2023 - 13 Jan 2023

Pharmacology/Drug Development


2023 Jan 10

Eur J Neurol

Response to erenumab assessed by HIT-6 is modulated by genetic factors and arterial hypertension – an explorative cohort study.


Zecca C, Terrazzino S, Para D, Campagna G, Viana M, Schankin CJ, Gobbi C
Eur J Neurol. 2023 Jan 10.
PMID: 36627267.


Response predictors to erenumab (ERE) in migraine patients would benefit their clinical management. We investigate associations between patients' clinic characteristics and polymorphisms at CALCRL and RAMP1 genes and response to ERE treatment measured as clinically meaningful improvement of the headache impact test 6 (HIT-6) score.