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Papers of the Week


2022 Dec


Open Heart


9


2

Lipid lowering with inclisiran: a real-world single-centre experience.

Authors

Padam P, Barton L, Wilson S, David A, Walji S, de Lorenzo F, Ray KK, Jones B, Cegla J
Open Heart. 2022 Dec; 9(2).
PMID: 36600646.

Abstract

The reduction in circulating low-density lipoprotein cholesterol (LDL-c) is the primary aim of lipid-lowering therapies as a method of atherosclerotic cardiovascular disease risk reduction. Inclisiran is a new and potent lipid-lowering drug that is shown to be effective in reducing LDL-c in randomised controlled trials, however, real-world data of its use are not yet known. We sought to analyse the early effects of this drug in a tertiary centre lipid and cardiovascular risk clinic.