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Papers of the Week

2022 Dec

Imaging Sci Dent



Mucormycosis-related osteomyelitis of the maxilla in a post-COVID-19 patient.


Kang Y-H, Lee S-S, Aung M T Z, Kang J-H, Kim J-E, Huh K-H, Heo M-S
Imaging Sci Dent. 2022 Dec; 52(4):435-440.
PMID: 36605866.


Mucormycosis is a rare, invasive fungal infection that progresses aggressively and requires prompt surgery and appropriate treatment. The number of cases of mucormycosis in coronavirus disease 2019 (COVID-19) patients has recently increased, and patients with uncontrolled diabetes mellitus are particularly at an elevated risk of infection. This report presents a case of mucormycosis-related osteomyelitis of the maxilla in a 37-year-old man with diabetes mellitus. The patient complained of severe and persistent pain in the right maxilla, accompanied by increased tooth mobility and headache. On contrast-enhanced computed tomographic images, gas-forming osteomyelitis of the right maxilla was observed. Destruction of the maxilla and palatine bone then proceeded aggressively. Sequestrectomy was performed on the right maxilla, and the histopathological diagnosis was mucormycosis. Further investigation after the first operation revealed the patient's history of COVID-19 infection.