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Papers of the Week

2022 Nov

Interdiscip Nurs Res



Trends of fecal calprotectin levels and associations with early life experience in preterm infants.


Xu W, Zhang Y, Zhao W, Chen J, Maas K, Hussain N, Henderson WA, Cong X
Interdiscip Nurs Res. 2022 Nov; 1(1):36-42.
PMID: 36590866.


Preterm infants are at risk for severe infections due to their immature immune systems. Factors such as early life pain/stress experiences and feeding may influence immune activation and maturation of immune systems. However, the underlying mechanism remains unclear. Fecal calprotectin (FCP) is a noninvasive surrogate biomarker of mucosal inflammation in the gastrointestinal tract and has been used in detecting intestinal inflammation in specific pediatric gastrointestinal disorders.