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Papers of the Week

2022 Dec 30

Int J Rheum Dis

Multiple joint dislocations and bone disintegration in rheumatoid arthritis: A case report.


Yuan X, Luo F, Li C, Hong X, Ma WK, Yao X
Int J Rheum Dis. 2022 Dec 30.
PMID: 36584982.


Rheumatoid arthritis (RA) is a chronic inflammatory disease, which typically affects the small joints of the hands and feet. Anti-rheumatism drugs should be promptly administered upon a diagnosis. Without standardized treatment, patients are prone to different degrees of deformities in the later stages of disease development, which negatively impact quality of life. We here report a case of a 52-year-old woman with an 18-year history of RA. After intermittent immunotherapy with anti-rheumatism drugs, the patient presented with multiple joint pain, dislocation, and disintegration of the bone. The interphalangeal joints of both hands were deformed to varying degrees and movement was significantly limited. After anti-rheumatism treatment, the patient experienced reduced joint pain. This case should enhance understanding and serve as a guide for patient management toward the prevention of joint deformities caused by RA.