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Papers of the Week

Papers: 24 Dec 2022 - 30 Dec 2022

2023 Jan 01

Korean J Pain



Primary somatosensory cortex and periaqueductal gray functional connectivity as a marker of the dysfunction of the descending pain modulatory system in fibromyalgia.


Soldatelli M, de Franco Á O, Picon F, Duarte J Á, Scherer R, Bandeira J, Zortea M, da Torres I L S, Fregni F, Caumo W
Korean J Pain. 2023 Jan 01; 36(1):113-127.
PMID: 36581601.


Resting-state functional connectivity (rs-FC) may aid in understanding the link between pain-modulating brain regions and the descending pain modulatory system (DPMS) in fibromyalgia (FM). This study investigated whether the differences in rs-FC of the primary somatosensory cortex in responders and non-responders to the conditioned pain modulation test (CPM-test) are related to pain, sleep quality, central sensitization, and the impact of FM on quality of life.