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Front Med (Lausanne)


Case report: Bullous pemphigoid arising in a patient with scleroderma and multiple sclerosis.


Moro F, Mariotti F, Pira A, De Luca N, Didona B, Pagnanelli G, Di Zenzo G
Front Med (Lausanne). 2022; 9:1055045.
PMID: 36569153.


Bullous pemphigoid (BP) is the most common autoimmune-blistering disease, clinically characterized by erythematous urticarial plaques, blisters, and intense pruritus, induced by autoantibodies against two proteins of the dermo-epidermal junction, BP180 and BP230. A large number of autoimmune diseases are reported in the literature as BP comorbidities, such as multiple sclerosis, but only a few cases are in association with scleroderma and none in association with both.